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MCM2 promotes the stemness and sorafenib resistance of hepatocellular carcinoma cells via hippo signaling

Object: A large number of studies have suggested that stemness is an essential mechanism for drug resistance, metastasis and relapse in hepatocellular carcinoma (HCC). The aim of this study was to determine the impact of MCM2 on stemness and identify potential mechanisms that complement the stemness...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Luo, Jianzhu, Xie, Haixiang, Wei, Zhongliu, Li, Tianman, Liu, Junqi, Liao, Xiwen, Zhu, Guangzhi, Peng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569387/
https://www.ncbi.nlm.nih.gov/pubmed/36243809
http://dx.doi.org/10.1038/s41420-022-01201-3