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MCM2 promotes the stemness and sorafenib resistance of hepatocellular carcinoma cells via hippo signaling
Object: A large number of studies have suggested that stemness is an essential mechanism for drug resistance, metastasis and relapse in hepatocellular carcinoma (HCC). The aim of this study was to determine the impact of MCM2 on stemness and identify potential mechanisms that complement the stemness...
Autores principales: | Zhou, Xin, Luo, Jianzhu, Xie, Haixiang, Wei, Zhongliu, Li, Tianman, Liu, Junqi, Liao, Xiwen, Zhu, Guangzhi, Peng, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569387/ https://www.ncbi.nlm.nih.gov/pubmed/36243809 http://dx.doi.org/10.1038/s41420-022-01201-3 |
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