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Selecting for CRISPR-Edited Knock-In Cells

CRISPR technology affords a simple and robust way to edit the genomes of cells, providing powerful tools for basic research and medicine. While using Cas9 to target a genomic site is very efficient, making a specific mutation at that site is much less so, as it depends on the endogenous DNA repair m...

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Detalles Bibliográficos
Autores principales: Reuven, Nina, Shaul, Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569436/
https://www.ncbi.nlm.nih.gov/pubmed/36233222
http://dx.doi.org/10.3390/ijms231911919