D121 Located within the DRY Motif of P2Y12 Is Essential for P2Y12-Mediated Platelet Function

Platelets are anucleate cells that mediate hemostasis. This occurs via a primary signal that is reinforced by secreted products such as ADP that bind purinergic receptors (P2Y1 and P2Y12) on the platelet surface. We recently identified a human subject, whom we termed platelet defect subject 25 (PDS2...

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Detalles Bibliográficos
Autores principales: Dangelmaier, Carol, Mauri, Benjamin, Patel, Akruti, Kunapuli, Satya P., Kostyak, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569438/
https://www.ncbi.nlm.nih.gov/pubmed/36232816
http://dx.doi.org/10.3390/ijms231911519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569438/
https://www.ncbi.nlm.nih.gov/pubmed/36232816
http://dx.doi.org/10.3390/ijms231911519

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