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D121 Located within the DRY Motif of P2Y12 Is Essential for P2Y12-Mediated Platelet Function
Platelets are anucleate cells that mediate hemostasis. This occurs via a primary signal that is reinforced by secreted products such as ADP that bind purinergic receptors (P2Y1 and P2Y12) on the platelet surface. We recently identified a human subject, whom we termed platelet defect subject 25 (PDS2...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569438/ https://www.ncbi.nlm.nih.gov/pubmed/36232816 http://dx.doi.org/10.3390/ijms231911519 |