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Novel Long-Acting Oxytocin Analog with Increased Efficacy in Reducing Food Intake and Body Weight

Oxytocin (OXT) analogues have been designed to overcome the limitation of the short half-life of the native OXT peptide. Here, we tested ASK2131 on obesity related outcomes in diet-induced obese (DIO) Sprague Dawley rats. In vitro function assays were conducted. The effects of daily subcutaneous inj...

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Detalles Bibliográficos
Autores principales: Elfers, Clinton T., Blevins, James E., Salameh, Therese S., Lawson, Elizabeth A., Silva, David, Kiselyov, Alex, Roth, Christian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569447/
https://www.ncbi.nlm.nih.gov/pubmed/36232550
http://dx.doi.org/10.3390/ijms231911249