Cargando…
Novel Long-Acting Oxytocin Analog with Increased Efficacy in Reducing Food Intake and Body Weight
Oxytocin (OXT) analogues have been designed to overcome the limitation of the short half-life of the native OXT peptide. Here, we tested ASK2131 on obesity related outcomes in diet-induced obese (DIO) Sprague Dawley rats. In vitro function assays were conducted. The effects of daily subcutaneous inj...
Autores principales: | Elfers, Clinton T., Blevins, James E., Salameh, Therese S., Lawson, Elizabeth A., Silva, David, Kiselyov, Alex, Roth, Christian L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569447/ https://www.ncbi.nlm.nih.gov/pubmed/36232550 http://dx.doi.org/10.3390/ijms231911249 |
Ejemplares similares
-
Robust Reductions of Body Weight and Food Intake by an Oxytocin Analog in Rats
por: Elfers, Clinton T., et al.
Publicado: (2021) -
Effects of Methylphenidate on Weight Gain and Food Intake in Hypothalamic Obesity
por: Elfers, Clinton Thomas, et al.
Publicado: (2011) -
Activation of nuclear factor kappa B pathway and reduction of hypothalamic oxytocin following hypothalamic lesions
por: Roth, Christian L., et al.
Publicado: (2016) -
Oxytocin reduces caloric intake in men
por: Lawson, Elizabeth A., et al.
Publicado: (2015) -
Central transthyretin acts to decrease food intake and body weight
por: Zheng, Fenping, et al.
Publicado: (2016)