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Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies

The search for an effective anti-viral to inhibit COVID-19 is a challenge for the specialized scientific research community. This work investigated the anti-coronavirus activity for spirooxindole-based phenylsulfone cycloadducts in a single and combination protocols. The newly designed anti-SARS-CoV...

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Detalles Bibliográficos
Autores principales: Barakat, Assem, Mostafa, Ahmed, Ali, M., Al-Majid, Abdullah Mohammed, Domingo, Luis R., Kutkat, Omnia, Moatasim, Yassmin, Zia, Komal, Ul-Haq, Zaheer, Elshaier, Yaseen A. M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569468/
https://www.ncbi.nlm.nih.gov/pubmed/36233160
http://dx.doi.org/10.3390/ijms231911861