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Collagen Type XI Inhibits Lung Cancer-Associated Fibroblast Functions and Restrains the Integrin Binding Site Availability on Collagen Type I Matrix

The tumor microenvironment, including cancer-associated fibroblast (CAF), plays an active role in non-small cell lung cancer (NSCLC) development and progression. We previously reported that collagen type XI and integrin α11, a collagen receptor, were upregulated in NSCLC; the latter promotes tumor g...

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Detalles Bibliográficos
Autores principales: Zeltz, Cédric, Khalil, Maryam, Navab, Roya, Tsao, Ming-Sound
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569509/
https://www.ncbi.nlm.nih.gov/pubmed/36233024
http://dx.doi.org/10.3390/ijms231911722