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Seq2Neo: A Comprehensive Pipeline for Cancer Neoantigen Immunogenicity Prediction

Neoantigens derived from somatic DNA alterations are ideal cancer-specific targets. In recent years, the combination therapy of PD-1/PD-L1 blockers and neoantigen vaccines has shown clinical efficacy in original PD-1/PD-L1 blocker non-responders. However, not all somatic DNA mutations result in immu...

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Detalles Bibliográficos
Autores principales: Diao, Kaixuan, Chen, Jing, Wu, Tao, Wang, Xuan, Wang, Guangshuai, Sun, Xiaoqin, Zhao, Xiangyu, Wu, Chenxu, Wang, Jinyu, Yao, Huizi, Gerarduzzi, Casimiro, Liu, Xue-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569519/
https://www.ncbi.nlm.nih.gov/pubmed/36232923
http://dx.doi.org/10.3390/ijms231911624