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Seq2Neo: A Comprehensive Pipeline for Cancer Neoantigen Immunogenicity Prediction
Neoantigens derived from somatic DNA alterations are ideal cancer-specific targets. In recent years, the combination therapy of PD-1/PD-L1 blockers and neoantigen vaccines has shown clinical efficacy in original PD-1/PD-L1 blocker non-responders. However, not all somatic DNA mutations result in immu...
Autores principales: | Diao, Kaixuan, Chen, Jing, Wu, Tao, Wang, Xuan, Wang, Guangshuai, Sun, Xiaoqin, Zhao, Xiangyu, Wu, Chenxu, Wang, Jinyu, Yao, Huizi, Gerarduzzi, Casimiro, Liu, Xue-Song |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569519/ https://www.ncbi.nlm.nih.gov/pubmed/36232923 http://dx.doi.org/10.3390/ijms231911624 |
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