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Mitochondrial DNA Repair in Neurodegenerative Diseases and Ageing

Mitochondria are the only organelles, along with the nucleus, that have their own DNA. Mitochondrial DNA (mtDNA) is a double-stranded circular molecule of ~16.5 kbp that can exist in multiple copies within the organelle. Both strands are translated and encode for 22 tRNAs, 2 rRNAs, and 13 proteins....

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Detalles Bibliográficos
Autores principales: Bazzani, Veronica, Equisoain Redin, Mara, McHale, Joshua, Perrone, Lorena, Vascotto, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569545/
https://www.ncbi.nlm.nih.gov/pubmed/36232693
http://dx.doi.org/10.3390/ijms231911391