Ribosomal RACK1 Regulates the Dendritic Arborization by Repressing FMRP Activity

FMRP is an RNA-binding protein that represses the translation of specific mRNAs. In neurons, its depletion determines the exaggerated translation of mRNAs leading to dendritic and axonal aberrant development, two peculiar features of Fragile X syndrome patients. However, how FMRP binds to translatio...

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Detalles Bibliográficos
Autores principales: Romano, Nicla, Di Giacomo, Bruna, Nobile, Veronica, Borreca, Antonella, Willems, Daniela, Tilesi, Francesca, Catalani, Elisabetta, Agrawal, Manasi, Welshhans, Kristy, Ricciardi, Sara, Cervia, Davide, Ceci, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569565/
https://www.ncbi.nlm.nih.gov/pubmed/36233159
http://dx.doi.org/10.3390/ijms231911857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569565/
https://www.ncbi.nlm.nih.gov/pubmed/36233159
http://dx.doi.org/10.3390/ijms231911857

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