Cargando…

Ribosomal RACK1 Regulates the Dendritic Arborization by Repressing FMRP Activity

FMRP is an RNA-binding protein that represses the translation of specific mRNAs. In neurons, its depletion determines the exaggerated translation of mRNAs leading to dendritic and axonal aberrant development, two peculiar features of Fragile X syndrome patients. However, how FMRP binds to translatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Romano, Nicla, Di Giacomo, Bruna, Nobile, Veronica, Borreca, Antonella, Willems, Daniela, Tilesi, Francesca, Catalani, Elisabetta, Agrawal, Manasi, Welshhans, Kristy, Ricciardi, Sara, Cervia, Davide, Ceci, Marcello
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569565/ https://www.ncbi.nlm.nih.gov/pubmed/36233159 http://dx.doi.org/10.3390/ijms231911857

Ejemplares similares

RACK1 regulates neural development
por: Kershner, Leah, et al.
Publicado: (2017)

RACK1 Is a Ribosome Scaffold Protein for β-actin mRNA/ZBP1 Complex
por: Ceci, Marcello, et al.
Publicado: (2012)

Local Translation Across Neural Development: A Focus on Radial Glial Cells, Axons, and Synaptogenesis
por: Agrawal, Manasi, et al.
Publicado: (2021)

RACK1 is evolutionary conserved in satellite stem cell activation and adult skeletal muscle regeneration
por: Catalani, Elisabetta, et al.
Publicado: (2022)

RACK1 on and off the ribosome
por: Johnson, Alex G., et al.
Publicado: (2019)

FMRP-Driven Neuropathology in Autistic Spectrum Disorder and Alzheimer's disease: A Losing Game
por: Bleuzé, Louis, et al.
Publicado: (2021)

Dscam1: Is It a Ubiquitous Code for Dendritic Arborization?
por: Kirkise, Nikita, et al.
Publicado: (2023)

RACK1 Specifically Regulates Translation through Its Binding to Ribosomes
por: Gallo, Simone, et al.
Publicado: (2018)

The ribosome-associated protein RACK1 represses Kir4.1 translation in astrocytes and influences neuronal activity
por: Oudart, Marc, et al.
Publicado: (2023)

Pumping the brakes: A noncanonical RNA-binding domain in FMRP stalls elongating ribosomes
por: Young-Baird, Sara K.
Publicado: (2022)

RACK1 depletion in the ribosome induces selective translation for non-canonical autophagy
por: Kim, Hag Dong, et al.
Publicado: (2017)

Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome
por: Rollins, Madeline G., et al.
Publicado: (2021)

FMRP Interacts with C/D Box snoRNA in the Nucleus and Regulates Ribosomal RNA Methylation
por: D'Souza, Michelle Ninochka, et al.
Publicado: (2018)

Ribosome profiling in mouse hippocampus: plasticity-induced regulation and bidirectional control by TSC2 and FMRP
por: Hien, Annie, et al.
Publicado: (2020)

Mammalian FMRP S499 Is Phosphorylated by CK2 and Promotes Secondary Phosphorylation of FMRP
por: Bartley, Christopher M., et al.
Publicado: (2016)

Heart regeneration is regulates by key micro RNAs from fish to mammals: what it can learned about the epicardial cells activation during the regeneration in zebrafish
por: Romano, Nicla, et al.
Publicado: (2018)

Local translation of cell adhesion molecules in axons
por: Jain, Shruti, et al.
Publicado: (2016)

FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism
por: Shah, Sneha, et al.
Publicado: (2020)

Diabetic retinopathy: a matter of retinal ganglion cell homeostasis
por: Catalani, Elisabetta, et al.
Publicado: (2020)

Novel emphasis on somatostatinergic system in retinal ganglion cell neuroresilience
por: Catalani, Elisabetta, et al.
Publicado: (2023)

Arbor.
Publicado: (1984)

Arbor.
Publicado: (1944)

The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans
por: Jannot, Guillaume, et al.
Publicado: (2011)

The ribosomal protein Asc1/RACK1 is required for efficient translation of short mRNAs
por: Thompson, Mary K, et al.
Publicado: (2016)

Ribosome-associated Asc1/RACK1 is required for endonucleolytic cleavage induced by stalled ribosome at the 3′ end of nonstop mRNA
por: Ikeuchi, Ken, et al.
Publicado: (2016)

Preparation and evaluation of wound healing activity of phytosomes of crocetin from Nyctanthes arbor-tristis in rats
por: Varadkar, Manasi, et al.
Publicado: (2021)

FMRP: a new chapter with chromatin
por: He, Qingzhong, et al.
Publicado: (2014)

Cellular localization of the FMRP in rat retina
por: Zhang, Ping-Ping, et al.
Publicado: (2020)

FMRP differentially regulates BK channels
por: Short, Ben
Publicado: (2020)

Neuroprotective Peptides in Retinal Disease
por: Cervia, Davide, et al.
Publicado: (2019)

A Drosophila perspective on retina functions and dysfunctions
por: Catalani, Elisabetta, et al.
Publicado: (2021)

Electronic racks for the trigger
por: M Droege
Publicado: (1991)

Gas distribution rack
Publicado: (1975)

Electronic racks of an experiment
por: CERN PhotoLab
Publicado: (1963)

Proteostasis Deregulation in Neurodegeneration and Its Link with Stress Granules: Focus on the Scaffold and Ribosomal Protein RACK1
por: Masi, Mirco, et al.
Publicado: (2022)

Asc1, homolog of human RACK1, prevents frameshifting in yeast by ribosomes stalled at CGA codon repeats
por: Wolf, Andrew S., et al.
Publicado: (2015)

The FMRP regulon: from targets to disease convergence
por: Fernández, Esperanza, et al.
Publicado: (2013)

FMRP: a triple threat to PSD-95
por: Westmark, Cara J.
Publicado: (2013)

Genetic association of FMRP targets with psychiatric disorders
por: Clifton, Nicholas E., et al.
Publicado: (2020)

Altered inflammatory response in FMRP-deficient microglia
por: Parrott, Jennifer M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5mr0m70rhu6f6ehbafgj9i8l1k