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Lipid Droplet Formation Is Regulated by Ser/Thr Phosphatase PPM1D via Dephosphorylation of Perilipin 1

Hypertrophy and hyperplasia of white adipocytes induce obesity, leading to diseases such as type 2 diabetes and hypertension, and even cancer. Hypertrophy of white adipocytes is attributed to the excessive storage of the energy form of triglycerides in lipid droplets (LDs). LDs are fat storage organ...

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Detalles Bibliográficos
Autores principales: Kamada, Rui, Uno, Sae, Kimura, Nozomi, Yoshimura, Fumihiko, Tanino, Keiji, Sakaguchi, Kazuyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569567/
https://www.ncbi.nlm.nih.gov/pubmed/36233344
http://dx.doi.org/10.3390/ijms231912046