Mutant Ataxin-2 Expression in Aged Animals Aggravates Neuropathological Features Associated with Spinocerebellar Ataxia Type 2

Spinocerebellar ataxia type 2 (SCA2) is a rare autosomal, dominantly inherited disease, in which the affected individuals have a disease onset around their third life decade. The molecular mechanisms underlying SCA2 are not yet completely understood, for which we hypothesize that aging plays a role...

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Detalles Bibliográficos
Autores principales: Afonso, Inês T., Lima, Patrícia, Conceição, André, Matos, Carlos A., Nóbrega, Clévio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569585/
https://www.ncbi.nlm.nih.gov/pubmed/36233198
http://dx.doi.org/10.3390/ijms231911896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569585/
https://www.ncbi.nlm.nih.gov/pubmed/36233198
http://dx.doi.org/10.3390/ijms231911896

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