Measurement of Hepatic CYP3A4 and 2D6 Activity Using Radioiodine-Labeled O-Desmethylvenlafaxine

Drug metabolizing enzyme activity is affected by various factors such as drug–drug interactions, and a method to quantify drug metabolizing enzyme activity in real time is needed. In this study, we developed a novel radiopharmaceutical for quantitative imaging to estimate hepatic CYP3A4 and CYP2D6 a...

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Detalles Bibliográficos
Autores principales: Mizutani, Asuka, Kobayashi, Masato, Aibe, Riku, Muranaka, Yuka, Nishi, Kodai, Kitamura, Masanori, Suzuki, Chie, Nishii, Ryuichi, Shikano, Naoto, Magata, Yasuhiro, Ishida, Yasushi, Kunishima, Munetaka, Kawai, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569593/
https://www.ncbi.nlm.nih.gov/pubmed/36232758
http://dx.doi.org/10.3390/ijms231911458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569593/
https://www.ncbi.nlm.nih.gov/pubmed/36232758
http://dx.doi.org/10.3390/ijms231911458

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