Novel Thieno [2,3-b]pyridine Anticancer Compound Lowers Cancer Stem Cell Fraction Inducing Shift of Lipid to Glucose Metabolism

Due to the role of cancer stem cells (CSCs) in tumor resistance and glycosphingolipid (GSL) involvement in tumor pathogenesis, we investigated the effect of a newly synthesized compound (3-amino-N-(3-chloro-2-methylphenyl)-5-oxo-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide 1 on the percent...

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Detalles Bibliográficos
Autores principales: Pervan, Matij, Marijan, Sandra, Markotić, Anita, Pilkington, Lisa I., Haverkate, Natalie A., Barker, David, Reynisson, Jóhannes, Meić, Luka, Radan, Mila, Čikeš Čulić, Vedrana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569594/
https://www.ncbi.nlm.nih.gov/pubmed/36232754
http://dx.doi.org/10.3390/ijms231911457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569594/
https://www.ncbi.nlm.nih.gov/pubmed/36232754
http://dx.doi.org/10.3390/ijms231911457

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