Evogliptin Directly Inhibits Inflammatory and Fibrotic Signaling in Isolated Liver Cells

Chronic liver inflammation can lead to fibrosis, cirrhosis, and hepatocellular carcinoma. Kupffer cells (KC) secrete proinflammatory and fibrogenic cytokines in response to lipopolysaccharide (LPS), and so play an important role in liver inflammation, where they induce hepatocellular damage. LPS als...

Descripción completa

Detalles Bibliográficos
Autores principales: Seo, Hye-Young, Lee, So-Hee, Han, Eugene, Hwang, Jae Seok, Han, Sol, Kim, Mi Kyung, Jang, Byoung Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569597/
https://www.ncbi.nlm.nih.gov/pubmed/36232933
http://dx.doi.org/10.3390/ijms231911636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569597/
https://www.ncbi.nlm.nih.gov/pubmed/36232933
http://dx.doi.org/10.3390/ijms231911636

Ejemplares similares