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Evogliptin Directly Inhibits Inflammatory and Fibrotic Signaling in Isolated Liver Cells
Chronic liver inflammation can lead to fibrosis, cirrhosis, and hepatocellular carcinoma. Kupffer cells (KC) secrete proinflammatory and fibrogenic cytokines in response to lipopolysaccharide (LPS), and so play an important role in liver inflammation, where they induce hepatocellular damage. LPS als...
Autores principales: | Seo, Hye-Young, Lee, So-Hee, Han, Eugene, Hwang, Jae Seok, Han, Sol, Kim, Mi Kyung, Jang, Byoung Kuk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569597/ https://www.ncbi.nlm.nih.gov/pubmed/36232933 http://dx.doi.org/10.3390/ijms231911636 |
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