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Bmal1 Regulates Prostate Growth via Cell-Cycle Modulation

The circadian clock system exists in most organs and regulates diverse physiological processes, including growth. Here, we used a prostate-specific Bmal1-knockout mouse model (pBmal1 KO: PbsnCre+; Bmal1(fx/fx)) and immortalized human prostate cells (RWPE-1 and WPMY-1) to elucidate the role of the pe...

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Detalles Bibliográficos
Autores principales: Ueda, Masakatsu, Kono, Jin, Sengiku, Atsushi, Nagumo, Yoshiyuki, Mathis, Bryan J., Shimba, Shigeki, Taketo, Makoto Mark, Kobayashi, Takashi, Ogawa, Osamu, Negoro, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569634/
https://www.ncbi.nlm.nih.gov/pubmed/36232573
http://dx.doi.org/10.3390/ijms231911272