Structural Insights into the Binding Propensity of Human SHIP2 SH2 to Oncogenic CagA Isoforms from Helicobacter pylori

SHIP2 is a multi-domain inositol 5-phosphatase binding to a variety of phosphotyrosine (pY)-containing proteins through its SH2 domain, so as to regulate various cell signaling pathways by modulating the phosphatidylinositol level in the plasma membrane. Unfavorably, Helicobacter pylori can hijack S...

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Detalles Bibliográficos
Autores principales: Wang, Zi, Shan, Yubao, Wang, Ru, Zhou, Heng, Hu, Rui, Li, Ying, Zhu, Jiang, Yang, Yunhuang, Liu, Maili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569640/
https://www.ncbi.nlm.nih.gov/pubmed/36232599
http://dx.doi.org/10.3390/ijms231911299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569640/
https://www.ncbi.nlm.nih.gov/pubmed/36232599
http://dx.doi.org/10.3390/ijms231911299

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