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CB(1) Ligand AM251 Induces Weight Loss and Fat Reduction in Addition to Increased Systemic Inflammation in Diet-Induced Obesity

Diet-induced obesity (DIO) reduces fatty acid oxidation in skeletal muscle and decreases circulating levels of adiponectin. Endocannabinoid signaling is overactive in obesity, with some effects abated by antagonism of cannabinoid receptor 1 (CB(1)). This research aimed to determine if treatment with...

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Detalles Bibliográficos
Autores principales: O’Keefe, Lannie, Vu, Teresa, Simcocks, Anna C., Jenkin, Kayte A., Mathai, Michael L., Hryciw, Deanne H., Hutchinson, Dana S., McAinch, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569643/
https://www.ncbi.nlm.nih.gov/pubmed/36232744
http://dx.doi.org/10.3390/ijms231911447