Crotalphine Modulates Microglia M1/M2 Phenotypes and Induces Spinal Analgesia Mediated by Opioid-Cannabinoid Systems

Pain is a worldwide public health problem and its treatment is still a challenge since clinically available drugs do not completely reverse chronic painful states or induce undesirable effects. Crotalphine is a 14 amino acids synthetic peptide that induces a potent and long-lasting analgesic effect...

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Detalles Bibliográficos
Autores principales: Lopes, Flavia S. R., Giardini, Aline C., Sant’Anna, Morena B., Kimura, Louise F., Bufalo, Michelle C., Vigerelli, Hugo, Zambelli, Vanessa O., Picolo, Gisele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569646/
https://www.ncbi.nlm.nih.gov/pubmed/36232883
http://dx.doi.org/10.3390/ijms231911571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569646/
https://www.ncbi.nlm.nih.gov/pubmed/36232883
http://dx.doi.org/10.3390/ijms231911571

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