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The Structural Effects of Phosphorylation of Protein Arginine Methyltransferase 5 on Its Binding to Histone H4

The protein arginine methyltransferase 5 (PRMT5) enzyme is responsible for arginine methylation on various proteins, including histone H4. PRMT5 is a promising drug target, playing a role in the pathomechanism of several diseases, especially in the progression of certain types of cancer. It was rece...

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Detalles Bibliográficos
Autores principales: Börzsei, Rita, Bayarsaikhan, Bayartsetseg, Zsidó, Balázs Zoltán, Lontay, Beáta, Hetényi, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569665/
https://www.ncbi.nlm.nih.gov/pubmed/36232624
http://dx.doi.org/10.3390/ijms231911316