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Mammary-Enriched Transcription Factors Synergize to Activate the Wap Super-Enhancer for Mammary Gland Development

Super-enhancers are large clusters of enhancers critical for cell-type-specific development. In a previous study, 440 mammary-specific super-enhancers, highly enriched for an active enhancer mark H3K27ac; a mediator MED1; and the mammary-enriched transcription factors ELF5, NFIB, STAT5A, and GR, wer...

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Detalles Bibliográficos
Autores principales: Kim, Uijin, Kim, Suyeon, Kim, Nahyun, Shin, Ha Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569684/
https://www.ncbi.nlm.nih.gov/pubmed/36232979
http://dx.doi.org/10.3390/ijms231911680