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Design, Synthesis and Biological Evaluation of Neocryptolepine Derivatives as Potential Anti-Gastric Cancer Agents

Natural products play an important role in drug development and lead compound synthesis. Neocryptolepine is a polycyclic quinoline compound isolated from Cryptolepis sanguinolent. The cytotoxicity of neocryptolepine to gastric cancer cells AGS, MKN45, HGC27, and SGC7901 was not very strong, and it a...

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Detalles Bibliográficos
Autores principales: Ma, Yunhao, Tian, Yanan, Zhou, Zhongkun, Chen, Shude, Du, Kangjia, Zhang, Hao, Jiang, Xinrong, Lu, Juan, Niu, Yuqing, Tu, Lixue, Wang, Jie, Liu, Huanxiang, Zhu, Hongmei, Chen, Peng, Liu, Yingqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569688/
https://www.ncbi.nlm.nih.gov/pubmed/36233226
http://dx.doi.org/10.3390/ijms231911924