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Design, Synthesis and Biological Evaluation of Neocryptolepine Derivatives as Potential Anti-Gastric Cancer Agents
Natural products play an important role in drug development and lead compound synthesis. Neocryptolepine is a polycyclic quinoline compound isolated from Cryptolepis sanguinolent. The cytotoxicity of neocryptolepine to gastric cancer cells AGS, MKN45, HGC27, and SGC7901 was not very strong, and it a...
Autores principales: | Ma, Yunhao, Tian, Yanan, Zhou, Zhongkun, Chen, Shude, Du, Kangjia, Zhang, Hao, Jiang, Xinrong, Lu, Juan, Niu, Yuqing, Tu, Lixue, Wang, Jie, Liu, Huanxiang, Zhu, Hongmei, Chen, Peng, Liu, Yingqian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569688/ https://www.ncbi.nlm.nih.gov/pubmed/36233226 http://dx.doi.org/10.3390/ijms231911924 |
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