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Long-Lasting Nociplastic Pain Modulation by Repeated Administration of Sigma-1 Receptor Antagonist BD1063 in Fibromyalgia-like Mouse Models

Sigma-1 receptor (σ1R) ligands have been shown to be effective at relieving neuropathic and inflammatory pain, but have not yet been tested in experimental models of fibromyalgia. The objective of this study was to evaluate the effect of a σ1R antagonist (BD1063) compared to pregabalin. ICR-CD1 fema...

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Detalles Bibliográficos
Autores principales: Álvarez-Pérez, Beltrán, Bagó-Mas, Anna, Deulofeu, Meritxell, Vela, José Miguel, Merlos, Manuel, Verdú, Enrique, Boadas-Vaello, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569697/
https://www.ncbi.nlm.nih.gov/pubmed/36233233
http://dx.doi.org/10.3390/ijms231911933