Prenatal SAMe Treatment Induces Changes in Brain Monoamines and in the Expression of Genes Related to Monoamine Metabolism in a Mouse Model of Social Hierarchy and Depression, Probably via an Epigenetic Mechanism

Reduction in the levels of monoamines, such as serotonin and dopamine in the brain, were reported in patients and animals with depression. SAMe, a universal methyl donor and an epigenetic modulator, is successfully used as an adjunct treatment of depression. We previously found that prenatal treatme...

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Detalles Bibliográficos
Autores principales: Becker, Maria, Abaev, Karin, Shmerkin, Elena, Weinstein-Fudim, Liza, Pinhasov, Albert, Ornoy, Asher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569718/
https://www.ncbi.nlm.nih.gov/pubmed/36233200
http://dx.doi.org/10.3390/ijms231911898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569718/
https://www.ncbi.nlm.nih.gov/pubmed/36233200
http://dx.doi.org/10.3390/ijms231911898

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