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Site-Specific Glycan Microheterogeneity Evaluation of Aflibercept Fusion Protein by Glycopeptide-Based LC-MSMS Mapping

The evaluation of the protein glycosylation states of samples of aflibercept obtained from three different regions was conducted by site-specific N-linked glycan microheterogeneity profiling. Glycopeptide-based nano-LC MSMS mapping of tryptic-digested samples of each aflibercept lot provided site-sp...

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Detalles Bibliográficos
Autores principales: Lee, Ju Yeon, Choi, Jin-Woong, Hwang, Seoyoung, Hahm, Sung Ho, Ahn, Yeong Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569749/
https://www.ncbi.nlm.nih.gov/pubmed/36233110
http://dx.doi.org/10.3390/ijms231911807