Selective Anti-Leishmanial Strathclyde Minor Groove Binders Using an N-Oxide Tail-Group Modification

The neglected tropical disease leishmaniasis, caused by Leishmania spp., is becoming more problematic due to the emergence of drug-resistant strains. Therefore, new drugs to treat leishmaniasis, with novel mechanisms of action, are urgently required. Strathclyde minor groove binders (S-MGBs) are an...

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Detalles Bibliográficos
Autores principales: Perieteanu, Marina C., McGee, Leah M. C., Shaw, Craig D., MacMillan, Donna S., Khalaf, Abedawn I., Gillingwater, Kirsten, Beveridge, Rebecca, Carter, Katharine C., Suckling, Colin J., Scott, Fraser J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569768/
https://www.ncbi.nlm.nih.gov/pubmed/36233213
http://dx.doi.org/10.3390/ijms231911912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569768/
https://www.ncbi.nlm.nih.gov/pubmed/36233213
http://dx.doi.org/10.3390/ijms231911912

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