Methionine γ-Lyase-Daidzein in Combination with S-Propyl-L-cysteine Sulfoxide as a Targeted Prodrug Enzyme System for Malignant Solid Tumor Xenografts

The purpose of this study was to determine the anticancer effect of dipropyl thiosulfinate produced in situ by the pharmacological pair: (1) conjugated with daidzein C115H methionine γ-lyase (EC 4.4.1.11, C115H MGL-Dz) and (2) the substrate, S-propyl-L-cysteine sulfoxide (propiin) against various so...

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Detalles Bibliográficos
Autores principales: Abo Qoura, Louay, Morozova, Elena, Kulikova, Vitalia, Karshieva, Saida, Sokolova, Darina, Koval, Vasiliy, Revtovich, Svetlana, Demidkina, Tatyana, Pokrovsky, Vadim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569779/
https://www.ncbi.nlm.nih.gov/pubmed/36233347
http://dx.doi.org/10.3390/ijms231912048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569779/
https://www.ncbi.nlm.nih.gov/pubmed/36233347
http://dx.doi.org/10.3390/ijms231912048

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