Methodological and Biological Factors Influencing Global DNA Methylation Results Measured by LINE-1 Pyrosequencing Assay in Colorectal Tissue and Liquid Biopsy Samples

Long interspersed nuclear element 1 (LINE-1) bisulfite pyrosequencing is a widely used technique for genome-wide methylation analyses. We aimed to investigate the effects of experimental and biological factors on its results to improve the comparability. LINE-1 bisulfite pyrosequencing was performed...

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Detalles Bibliográficos
Autores principales: Szigeti, Krisztina A, Barták, Barbara K, Nagy, Zsófia B, Zsigrai, Sára, Papp, Márton, Márkus, Eszter, Igaz, Peter, Takács, István, Molnár, Béla, Kalmár, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569782/
https://www.ncbi.nlm.nih.gov/pubmed/36232908
http://dx.doi.org/10.3390/ijms231911608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569782/
https://www.ncbi.nlm.nih.gov/pubmed/36232908
http://dx.doi.org/10.3390/ijms231911608

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