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Genetic Ablation of Nrf2 Exacerbates Neuroinflammation in Ocular Autoimmunity

Experimental autoimmune uveoretinitis (EAU) is an animal model of non-infectious uveitis and is developed by immunization with retinal antigen, interphotoreceptor retinoid-binding protein (IRBP). Nuclear factor erythroid 2- (NF-E2-) related factor 2 (Nrf2) is responsible for regulating antioxidant a...

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Detalles Bibliográficos
Autores principales: Sato, Yasuhiko, Saito, Shoko, Nakayama, Makiko, Sugita, Sunao, Kudo, Akihiko, Keino, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569802/
https://www.ncbi.nlm.nih.gov/pubmed/36233013
http://dx.doi.org/10.3390/ijms231911715