Proviral ALV-LTR Sequence Is Essential for Continued Proliferation of the ALV-Transformed B Cell Line

Avian leukosis virus (ALV) induces B-cell lymphomas and other malignancies in chickens through insertional activation of oncogenes, and c-myc activation has been commonly identified in ALV-induced tumors. Using ALV-transformed B-lymphoma-derived HP45 cell line, we applied in situ CRISPR-Cas9 editing...

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Detalles Bibliográficos
Autores principales: Roy, Swagata, Bondada, Megha Sravani, Zhang, Yaoyao, Moffat, Katy, Nair, Venugopal, Yao, Yongxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569804/
https://www.ncbi.nlm.nih.gov/pubmed/36232572
http://dx.doi.org/10.3390/ijms231911263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569804/
https://www.ncbi.nlm.nih.gov/pubmed/36232572
http://dx.doi.org/10.3390/ijms231911263

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