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Effects of RAGE Deletion on the Cardiac Transcriptome during Aging

Cardiac aging is characterized by increased cardiomyocyte hypertrophy, myocardial stiffness, and fibrosis, which enhance cardiovascular risk. The receptor for advanced glycation end-products (RAGE) is involved in several age-related diseases. RAGE knockout (Rage−/−) mice show an acceleration of card...

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Detalles Bibliográficos
Autores principales: Scavello, Francesco, Piacentini, Luca, Castiglione, Stefania, Zeni, Filippo, Macrì, Federica, Casaburo, Manuel, Vinci, Maria Cristina, Colombo, Gualtiero I., Raucci, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569842/
https://www.ncbi.nlm.nih.gov/pubmed/36232442
http://dx.doi.org/10.3390/ijms231911130