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Effects of RAGE Deletion on the Cardiac Transcriptome during Aging
Cardiac aging is characterized by increased cardiomyocyte hypertrophy, myocardial stiffness, and fibrosis, which enhance cardiovascular risk. The receptor for advanced glycation end-products (RAGE) is involved in several age-related diseases. RAGE knockout (Rage−/−) mice show an acceleration of card...
Autores principales: | Scavello, Francesco, Piacentini, Luca, Castiglione, Stefania, Zeni, Filippo, Macrì, Federica, Casaburo, Manuel, Vinci, Maria Cristina, Colombo, Gualtiero I., Raucci, Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569842/ https://www.ncbi.nlm.nih.gov/pubmed/36232442 http://dx.doi.org/10.3390/ijms231911130 |
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