27-Hydroxycholesterol-Induced Dysregulation of Cholesterol Metabolism Impairs Learning and Memory Ability in ApoE ε4 Transgenic Mice

Dysregulated brain cholesterol metabolism is one of the characteristics of Alzheimer’s disease (AD). 27-Hydroxycholesterol (27-OHC) is a cholesterol metabolite that plays an essential role in regulating cholesterol metabolism and it is suggested that it contributes to AD-related cognitive deficits....

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Detalles Bibliográficos
Autores principales: Wang, Yushan, Hao, Ling, Wang, Tao, Liu, Wen, Wang, Lijing, Ju, Mengwei, Feng, Wenjing, Xiao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569856/
https://www.ncbi.nlm.nih.gov/pubmed/36232940
http://dx.doi.org/10.3390/ijms231911639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569856/
https://www.ncbi.nlm.nih.gov/pubmed/36232940
http://dx.doi.org/10.3390/ijms231911639

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