Saposin C, Key Regulator in the Alpha-Synuclein Degradation Mediated by Lysosome

Lysosomal dysfunction has been proposed as one of the most important pathogenic molecular mechanisms in Parkinson disease (PD). The most significant evidence lies in the GBA gene, which encodes for the lysosomal enzyme β-glucocerebrosidase (β-GCase), considered the main genetic risk factor for spora...

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Detalles Bibliográficos
Autores principales: Ruz, Clara, Barrero, Francisco J., Pelegrina, Javier, Bandrés-Ciga, Sara, Vives, Francisco, Duran, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569857/
https://www.ncbi.nlm.nih.gov/pubmed/36233303
http://dx.doi.org/10.3390/ijms231912004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569857/
https://www.ncbi.nlm.nih.gov/pubmed/36233303
http://dx.doi.org/10.3390/ijms231912004

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