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Hepatoprotective Effects of a Natural Flavanol 3,3′-Diindolylmethane against CCl(4)-Induced Chronic Liver Injury in Mice and TGFβ1-Induced EMT in Mouse Hepatocytes via Activation of Nrf2 Cascade

Hepatic fibrosis is a form of irregular wound-healing response with acute and chronic injury triggered by the deposition of excessive extracellular matrix. Epithelial–mesenchymal transition (EMT) is a dynamic process that plays a crucial role in the fibrogenic response and pathogenesis of liver fibr...

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Detalles Bibliográficos
Autores principales: Munakarmi, Suvesh, Gurau, Yamuna, Shrestha, Juna, Risal, Prabodh, Park, Ho Sung, Shin, Hyun Beak, Jeong, Yeon Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569868/
https://www.ncbi.nlm.nih.gov/pubmed/36232707
http://dx.doi.org/10.3390/ijms231911407