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Intestinal Epithelial STAT6 Activation Rescues the Defective Anti-Helminth Responses Caused by Ogt Deletion

Dynamic regulation of intestinal epithelial cell (IEC) proliferation and differentiation is crucial for maintaining mucosa homeostasis and the response to helminth infection. O-GlcNAc transferase (OGT), an enzyme catalyzing the transfer of GlcNAc from the donor substrate UDP-GlcNAc onto acceptor pro...

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Detalles Bibliográficos
Autores principales: Xiong, Xiwen, Huang, Rong, Li, Zun, Yang, Chenyan, Wang, Qingzhi, Ruan, Hai-Bin, Xu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569950/
https://www.ncbi.nlm.nih.gov/pubmed/36232438
http://dx.doi.org/10.3390/ijms231911137