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The Interplay between GSK3β and Tau Ser262 Phosphorylation during the Progression of Tau Pathology

Tau hyperphosphorylation has been linked directly to the formation of toxic neurofibrillary tangles (NFTs) in tauopathies, however, prior to NFT formation, the sequence of pathological events involving tau phosphorylation remains unclear. Here, the effect of glycogen synthase kinase 3β (GSK3β) on ta...

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Detalles Bibliográficos
Autores principales: Song, Liqing, Oseid, Daniel E., Wells, Evan A., Robinson, Anne Skaja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569960/
https://www.ncbi.nlm.nih.gov/pubmed/36232909
http://dx.doi.org/10.3390/ijms231911610