Haloperidol-Induced Immediate Early Genes in Striatopallidal Neurons Requires the Converging Action of cAMP/PKA/DARPP-32 and mTOR Pathways

Antipsychotics share the common pharmacological feature of antagonizing the dopamine 2 receptor (D2R), which is abundant in the striatum and involved in both the therapeutic and side effects of this drug’s class. The pharmacological blockade of striatal D2R, by disinhibiting the D2R-containing mediu...

Descripción completa

Detalles Bibliográficos
Autores principales: Onimus, Oriane, Valjent, Emmanuel, Fisone, Gilberto, Gangarossa, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569967/
https://www.ncbi.nlm.nih.gov/pubmed/36232936
http://dx.doi.org/10.3390/ijms231911637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569967/
https://www.ncbi.nlm.nih.gov/pubmed/36232936
http://dx.doi.org/10.3390/ijms231911637

Ejemplares similares