TRAIL-R Deficient Mice Are Protected from Neurotoxic Effects of Amyloid-β

TRAIL, a member of TNF superfamily, is a potent inducer of neuronal death. Neurotoxic effects of TRAIL appear mediated by its death receptor TRAIL-R2/DR5. To assess the role of TRAIL/TRAIL-R2 pathway in AD-related neurodegeneration, we studied the impact of the treatment with amyloid-β (Aβ) upon cel...

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Detalles Bibliográficos
Autores principales: Di Benedetto, Giulia, Burgaletto, Chiara, Serapide, Maria Francesca, Caltabiano, Rosario, Munafò, Antonio, Bellanca, Carlo Maria, Di Mauro, Rosaria, Bernardini, Renato, Cantarella, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569968/
https://www.ncbi.nlm.nih.gov/pubmed/36232931
http://dx.doi.org/10.3390/ijms231911625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569968/
https://www.ncbi.nlm.nih.gov/pubmed/36232931
http://dx.doi.org/10.3390/ijms231911625

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