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TRAIL-R Deficient Mice Are Protected from Neurotoxic Effects of Amyloid-β

TRAIL, a member of TNF superfamily, is a potent inducer of neuronal death. Neurotoxic effects of TRAIL appear mediated by its death receptor TRAIL-R2/DR5. To assess the role of TRAIL/TRAIL-R2 pathway in AD-related neurodegeneration, we studied the impact of the treatment with amyloid-β (Aβ) upon cel...

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Detalles Bibliográficos
Autores principales:	Di Benedetto, Giulia, Burgaletto, Chiara, Serapide, Maria Francesca, Caltabiano, Rosario, Munafò, Antonio, Bellanca, Carlo Maria, Di Mauro, Rosaria, Bernardini, Renato, Cantarella, Giuseppina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569968/ https://www.ncbi.nlm.nih.gov/pubmed/36232931 http://dx.doi.org/10.3390/ijms231911625

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