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Metabolic Heterogeneity of Brain Tumor Cells of Proneural and Mesenchymal Origin

Brain-tumor-initiating cells (BTICs) of proneural and mesenchymal origin contribute to the highly malignant phenotype of glioblastoma (GB) and resistance to current therapies. BTICs of different subtypes were challenged with oxidative phosphorylation (OXPHOS) inhibition with metformin to assess the...

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Detalles Bibliográficos
Autores principales: Seliger, Corinna, Meyer, Anne-Louise, Leidgens, Verena, Rauer, Lisa, Moeckel, Sylvia, Jachnik, Birgit, Proske, Judith, Dettmer, Katja, Rothhammer-Hampl, Tanja, Kaulen, Leon D., Riemenschneider, Markus J., Oefner, Peter J., Kreutz, Marina, Schmidt, Nils-Ole, Merrill, Marsha, Uhl, Martin, Renner, Kathrin, Vollmann-Zwerenz, Arabel, Proescholdt, Martin, Hau, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569970/
https://www.ncbi.nlm.nih.gov/pubmed/36232951
http://dx.doi.org/10.3390/ijms231911629