The Novel Small Molecule BTB Inhibits Pro-Fibrotic Fibroblast Behavior though Inhibition of RhoA Activity

Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic, interstitial lung disease with a poor prognosis. Although specific anti-fibrotic medications are now available, the median survival time following diagnosis remains very low, and new therapies are urgently needed. To uncover novel therap...

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Detalles Bibliográficos
Autores principales: Rackow, Ashley R., Nagel, David J., Zapas, Gregory, Clough, Ryan S., Sime, Patricia J., Kottmann, R. Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569993/
https://www.ncbi.nlm.nih.gov/pubmed/36233248
http://dx.doi.org/10.3390/ijms231911946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569993/
https://www.ncbi.nlm.nih.gov/pubmed/36233248
http://dx.doi.org/10.3390/ijms231911946

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