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The Novel Small Molecule BTB Inhibits Pro-Fibrotic Fibroblast Behavior though Inhibition of RhoA Activity
Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic, interstitial lung disease with a poor prognosis. Although specific anti-fibrotic medications are now available, the median survival time following diagnosis remains very low, and new therapies are urgently needed. To uncover novel therap...
Autores principales: | Rackow, Ashley R., Nagel, David J., Zapas, Gregory, Clough, Ryan S., Sime, Patricia J., Kottmann, R. Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569993/ https://www.ncbi.nlm.nih.gov/pubmed/36233248 http://dx.doi.org/10.3390/ijms231911946 |
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