Impairment of Nucleolin Activity and Phosphorylation by a Trachylobane Diterpene from Psiadia punctulata in Cancer Cells

Human nucleolin (hNcl) is a multifunctional protein involved in the progression of various cancers and plays a key role in other pathologies. Therefore, there is still unsatisfied demand for hNcl modulators. Recently, we demonstrated that the plant ent-kaurane diterpene oridonin inhibits hNcl but, u...

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Detalles Bibliográficos
Autores principales: Bellone, Maria Laura, Fiengo, Lorenzo, Cerchia, Carmen, Cotugno, Roberta, Bader, Ammar, Lavecchia, Antonio, De Tommasi, Nunziatina, Piaz, Fabrizio Dal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570042/
https://www.ncbi.nlm.nih.gov/pubmed/36232690
http://dx.doi.org/10.3390/ijms231911390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570042/
https://www.ncbi.nlm.nih.gov/pubmed/36232690
http://dx.doi.org/10.3390/ijms231911390

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